George Vanderbilt's 250-room French Renaissance chateau, completed in 1895, remains America's largest privately owned home. Today's estate spans 8,000 acres including the house with original furnishings and art, 75 acres of Frederick Law Olmsted-designed gardens, a working winery with tastings, restaurants, and shops. Allow a full day. 6+ hours of content exists. The 90-minute drive from the Smokies is straightforward. Advance tickets required; prices vary seasonally. Christmas at Biltmore (November-January) adds elaborate decorations and evening candlelight tours.